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<p class="MsoTitle" style="line-height:50%;"><span lang="EN-US" style="font-size:14.0pt;line-height:50%;font-family:"Times New Roman"">Chlorogenic Acid Powder<o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-pagination:widow-orphan;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;"><b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">Active Ingredients</span></b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning: 0pt">:<b> </b>Chlorogenic Acid<o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">Specification:</span></b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;"> Chlorogenic Acid 25% HPLC ro 4%-99% Chlorogenic Acid</span><span lang="EN-US"><br /> <o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="margin-left:5.15pt;text-align:left;text-indent:-5.15pt;mso-char-indent-count:-.49;line-height:75%;"><b><span lang="EN-US">Appearance:</span></b><span lang="EN-US"> Brownish yellow powder for 25%<o:p></o:p></span></p> <div class="MsoNormal" align="center" style="margin-left:5.15pt;text-align:center;text-indent:-5.15pt;mso-char-indent-count:-.49;line-height:75%;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US">Botanical Source: </span></b><span lang="EN-US">Flower of Lonicera japonica Thunb. Or Lonicera acuminata.Wall. <o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US">Molecular Formula</span></b><span lang="EN-US">: </span><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">C<sub>16</sub>H<sub>18</sub>O<sub>9</sub><o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">Molecular Mass</span></b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">: 354.31<o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">CAS No.</span></b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">: 327-97-9 <o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">Melting Point:</span></b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;"> 205<st1:chmetcnv unitname="°C" sourcevalue="209" hasspace="False" negative="True" numbertype="1" tcsc="0" w:st="on">-209°C</st1:chmetcnv><o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">Alpha</span></b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">: -36 º (c=1, H2O) <o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">Water solubility</span></b><span lang="EN-US" style="mso-bidi-font-size:10.0pt;line-height:75%;mso-font-kerning:0pt;">: Soluble in hot water<o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="center" style="text-align:center;line-height:75%;"><b><span lang="EN-US"><o:p> <img src="/images/Chlorogenic Acid.JPG" title="Chlorogenic Acid" alt="Chlorogenic Acid" /></o:p></span></b></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US">Pharmacology Action<o:p></o:p></span></b></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:150%;"><span lang="EN-US">1) Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major phenolic compound in coffee, but is also found widespread in plants and can be isolated from the leaves and fruit. </span></p> <p class="MsoNormal" align="left" style="text-align:left;line-height:150%;"><span lang="EN-US">2) This acid is an important factor in plant metabolism. </span></p> <p class="MsoNormal" align="left" style="text-align:left;line-height:150%;"><span lang="EN-US">3) It is also an antioxidant and an inhibitor of the tumor promoting activity of phorbol esters; at concentrations as high as 100 μg/L, does not inhibit the 5-lipoxygenase activity of ionophore-stimulated human polymorphonuclear leukocytes. </span></p> <p class="MsoNormal" align="left" style="text-align:left;line-height:150%;"><span lang="EN-US">4) Chlorogenic acid and caffeic acid are antioxidants in vitro and might therefore contribute to the prevention of Type 2 Diabetes Mellitus and cardiovascular disease . <o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:150%;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;"><b><span lang="EN-US">Application:<o:p></o:p></span></b></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:150%;"><span lang="EN-US">-Treatment Gastrointestinal cancer and leukemia,</span></p> <p class="MsoNormal" align="left" style="text-align:left;line-height:150%;"><span lang="EN-US">-Plant growth regulator activity and kill insects.<span> </span></span></p> <p class="MsoNormal" align="left" style="text-align:left;line-height:150%;"><span lang="EN-US">-Treatment of gastric cancer, liver cancer, head and neck cancer and leukemia,, with fewer side effects than camptothecine.</span></p> <div class="MsoNormal" align="center" style="text-align:center;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US"> <hr size="2" width="100%" align="center" /> </span></div>