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<p class="MsoNormal" align="center" style="text-align:left;line-height:75%;"><a name="OLE_LINK14"></a><a name="OLE_LINK13"></a><a name="OLE_LINK11"></a><a name="OLE_LINK9"></a><a name="OLE_LINK5"></a><a name="OLE_LINK7"></a><a name="OLE_LINK8"></a><a name="OLE_LINK6"></a><a name="OLE_LINK3"></a><a name="OLE_LINK20"></a><a name="OLE_LINK15"></a><a name="OLE_LINK12"></a><a name="OLE_LINK4"><b><span lang="EN-US" style="font-size:14.0pt;line-height:75%;">Hesperitin Powder</span></b></a><b><span lang="EN-US" style="font-size:14.0pt;line-height:75%;"><o:p></o:p></span></b></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-pagination:widow-orphan;"><a name="OLE_LINK22"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height: 75%"> <hr size="2" width="100%" align="center" /> </span></a></div> <p class="MsoNormal" style="line-height:75%;mso-pagination:widow-orphan;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;">Active Ingredients:</span></b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> Hesperitin<o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-pagination:widow-orphan;"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" style="line-height:75%;mso-pagination:widow-orphan;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;mso-font-kerning: 0pt">Specification: </span></b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;mso-font-kerning:0pt;">90%, 95%, 98% by HPLC<o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-pagination:widow-orphan;"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" style="line-height:75%;mso-pagination:widow-orphan;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;">Appearance:</span></b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> yellow needle <o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-pagination:widow-orphan;"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;">Molecular Formula</span></b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;">: <span class="apple-style-span"><span style="background-image:initial;background-attachment:initial;background-origin:initial;background-clip:initial;background-color:white;background-position:initial initial;background-repeat:initial initial;">C<sub>16</sub>H<sub>14</sub>O<sub>6</sub></span></span><o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;">Molecular Weight: </span></b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;">302.29<o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" style="line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;mso-font-kerning:0pt;">CAS No.:</span></b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;mso-font-kerning:0pt;"> 520-33-2<o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><a name="OLE_LINK2"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height: 75%"> <hr size="2" width="100%" align="center" /> </span></a></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;">Melting Point:</span></b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> 226<st1:chmetcnv unitname="℃" sourcevalue="228" hasspace="False" negative="True" numbertype="1" tcsc="0" w:st="on">-228<span lang="EN-US" style="font-family:宋体;mso-ascii-font-family:"Times New Roman";mso-hansi-font-family:"Times New Roman""><span lang="EN-US">℃</span></span></st1:chmetcnv><o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><a name="OLE_LINK19"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height: 75%"> <hr size="2" width="100%" align="center" /> </span></a></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;">Herb source:</span></b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> Citrus sinensis<o:p></o:p></span></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;">Molecular Structure: <o:p></o:p></span></b></p> <p class="MsoNormal" align="left" style="text-align:center;line-height:75%;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"><o:p> <img src="/images/Hesperitin.jpg" alt="" /></o:p></span></b></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;"> <hr size="2" width="100%" align="center" /> </span></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:75%;mso-layout-grid-align:none;text-autospace:none;"><b><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:75%;mso-font-kerning:0pt;">Function: <o:p></o:p></span></b></p> <div class="MsoNormal" align="center" style="text-align:center;line-height:150%;"><a name="OLE_LINK1"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:150%;"> <hr size="2" width="100%" align="center" /> </span></a></div> <p class="MsoNormal" align="left" style="text-align:left;line-height:150%;"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:150%;">Hesperetin is a citrus flavonoid that has been reported to lower plasmacholesterol. Hesperetin reduces the transcription of ACAT-2 mRNA in HepG2 cells and reduces ApoB protein synthesis in a dose-dependent manner. The EC50 for these responses is approximately 50 μ M. </span><span lang="EN-US" style="line-height:150%;">Hesperetin also inhibits histamine release from IgE-challenged RBL-2H3 cells, with a potency </span>comparable to the commercial anti-allergy drug azelastine.</p> <div class="MsoNormal" align="center" style="text-align:center;line-height:150%;"><span lang="EN-US" style="mso-bidi-font-size:10.5pt;line-height:150%;"> <hr size="2" width="100%" align="center" /> </span></div>