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<a name="OLE_LINK11"></a><a name="OLE_LINK9"></a><a name="OLE_LINK5"></a><a name="OLE_LINK7"></a><a name="OLE_LINK8"></a><a name="OLE_LINK6"></a><a name="OLE_LINK3"></a><a name="OLE_LINK4">Piperine Powder</a><o:p></o:p>
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Active Ingredients: Piperine<o:p></o:p>
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Specification: <a name="OLE_LINK2">90%, 95%, 98%
by HPLC</a><o:p></o:p>
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Appearance: yellow to white crystal powder&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <o:p></o:p>
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Botanical Source: Piper nigrum L. <o:p></o:p>
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Molecular Formula: <span style="background-image:initial;background-attachment:initial;background-origin:initial;background-clip:initial;background-color:white;background-position:initial initial;background-repeat:initial initial;">&nbsp;<span style="background-image:initial;background-attachment:initial;background-origin:initial;background-clip:initial;background-color:white;background-position:initial initial;background-repeat:initial initial;">C17H19NO3<o:p></o:p>
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Molecular Weight: 285.3377<o:p></o:p>
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CAS No.: 94-62-2<o:p></o:p>
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Melting Point: <st1:chmetcnv unitname="℃" sourcevalue="129" hasspace="False" negative="False" numbertype="1" tcsc="0" w:st="on">129℃</st1:chmetcnv><o:p></o:p>
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Function: <o:p></o:p>
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 <a name="OLE_LINK14">1 Piperine is often added to prepared food to enhance aroma and flavor.It
can Promote drug absorption, and improve the effectiveness of the drug
function. In clinical practice, it can induce calm (sedative effect) or to
induce sleep (hypnotic effect), and used to make anticonvulsant,
antidepressant, and muscle relaxation drug.<o:p></o:p></a>
2 Piperine has also been found to inhibit human CYP<st1:chmetcnv unitname="a" sourcevalue="3" hasspace="False" negative="False" numbertype="1" tcsc="0" w:st="on">3A</st1:chmetcnv>4 and P-glycoprotein, enzymes important for
the metabolism and transport of xenobiotics and metabolites.In animal studies,
piperine also inhibited other enzymes important in drug metabolism. By
inhibiting drug metabolism, piperine may increase the bioavailability of
various compounds and alter the effectiveness of some medications. Notably,
piperine may enhance bioavailability of curcumin by 2000% in humans.<o:p></o:p>
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